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Keratosis palmoplantaris diffusa (Rudiment)
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Keratosis palmoplantaris diffusa (Rudiment)
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Ätiologie |
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Risikofaktoren |
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Vererbung |
autosomal dominant (beide Formen) |
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OMIM |
144200 (Vörner-Unna-Thost) |
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148500 (Tylosis) |
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Chromosom |
17q24 (Tyleosis) |
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Pathogenese |
Vörner-Unna-Thost: Keratin-9-Gen (nur palmoplantar exprimiert) |
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Makroskopie |
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Mikroskopie |
Orthohyperkeratose, Akanthose, fokale granuläre Degenerationen |
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