 |
 |
 |
|
 |
|
 |
 |
 |
 |
 |
Acemetacin
|
| |||||||||||
|
| ||||||||||||
|
Acemetacin
|
||||||||||||
|
| Pharmakokinetik | ||
Allgemeines |
|
|
 |
||
Bioverfügbarkeit |
100 % |
|
|
||
Verteilungsvolumen |
1 l/kg |
|
|
||
Plasmaproteinbindung |
90 % |
|
|
||
Liquor |
|
|
|
||
Metabolisierung |
|
|
|
||
totale Clearance |
|
|
|
||
Halbwertszeit |
4,5 h (aktiver Metabolit 6 h) |
|
|
||
Q0 |
0,6 (aktiver Metabolit 0,85) |
|
|
||
Elimination |
|
|
|
||
Dialysierbarkeit |
|
|
|
||
| ||
| |||
